Fluorescent SRfluor Dyes_updated, 680 Phenyl dye
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Fluorescent SRfluor? Dyes_updated, 680 Phenyl dye 원적외선 영역의 스펙트럼이 있는 형광 색소입니다
SRfluor는 Molecular Targeting Technologies 사가 독자적으로 개발한 Squaraine Rotaxanes 계의 적색 형광 색소 입니다. Rotaxanes은 축 모양의 기본 골격에 큰 환상 구조의 분자가 관통한 분자 집합체이며, SRfluor는 이 구조에 의해 형광의 안정화가 도모되고, 퇴색하기 않는 성질을 가지고 있습니다. Cy 염료와 Alexa Fluor (R) 색소보다 형광 강도가 높고, 안정성이 뛰어납니다. 원적외선 영역에 sharp한 스펙트럼을 가지고 있어 in vivo imaging에도 유용합니다.
Advantages of SRfluor? Dyes : • Improved chemical and photochemical stability compared with squaraines, cyanines, Alexa? and Atto dyes • Exhibit sharp absorption and emission bands thus provide reduced excitation and emission cross talk into channels where other fluorochromes are being used. • Do not exhibit aggregation induced spectral broadening under biological conditions at micromolar concentrations. • 5-20X brighter compared with cyanines, Alexa? and Atto dyes. • Photophysical properties stable over the pH range from 2-12. • Spectral properties compatible with the 633nm or 647nm laser lines on flow cytometers, confocal and in vivo imaging equipment.
※ DMSO에 녹여 사용합니다 (DMSO는 별도로 준비하시기 바랍니다.)
Figure 1: Fluorescence microscopy images of live mammalian cells treated with SRfluor 680 Phenyl. (A) Endoplasmic- Reticulum staining of a single CHO cell. (B) Lipid droplet staining in A549 cells.
Figure 2: Optical image of a live mouse with subcutaneous injections of S. aureus and E. coli that were prelabeled with SRfluor?probe. The entire animal was irradiated with filtered light at λ = 625 ± 40 nm and an image with emission intensity at λ = 670 ± 20 nm was collected by a CCD camera during a 5 s acquisition period. Image courtesy of Professor Bradley Smith, University of Notre Dame, Indiana, USA.
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Ordering informations
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Catalog No. |
Name |
Description |
Size |
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SR-1001 |
SRfluor? 680 Phenyl Crystalline Powder |
Lipophilic squaraine rotaxane analog that emits in the far-red region of the spectrum and is known to accumulate at lipophilic sites inside living cells. Spectral properties: abs max = 650 nm and emission max = 678 nm in DMSO.
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1mg |
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SR-1004 |
SRfluor? malemide |
A far-red emitting dye, belonging to the squaraine rotaxane family of dyes, which bears a maleimide functionality.
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1mg |
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SR-1006 |
SRfluor? 680 azide carboxylate Crystalline Powder |
Squaraine rotaxane analog that emits in the far-red region of the spectrum and is functionalized with an azide group that can readily undergo click chemistry reactions with rea-gents or biomolecules with a terminal alkyne group to pro-vide fluorescent conjugates for use in multiple applications. A free carboxyl group is also present in this molecule which can be coupled to amino groups of biomolecules. Spectral properties: abs max = 645 nm and emission max = 668 nm in DMSO.
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1mg |
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SR-1007 |
SRfluor? 680 alkyne Crystalline Powder |
Squaraine rotaxane analog that emits in the far-red region of the spectrum and is functionalized with a terminal alkyne group that can readily undergo click chemistry reactions with reagents or biomolecules with an azide group to pro-vide fluorescent conjugates for use in multiple applications. Spectral properties: abs max = 649 nm and emission max = 673 nm in DMSO.
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1mg |
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SR-1010 |
Micellar SRfluor? 680 Phenyl dye |
Provides an aqueous formulation of the lipophilic squaraine rotaxane dye, SRfluor? 680 phenyl, in micelles composed of DPPE-PEG2000 which is known to accumu-late in interscapular brown adipose tissue in mice. Spectral properties: abs max = 646 nm and emission max = 670 nm in DMSO.
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100 nmoles |
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