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Succinimidyl 6-hydrazinonicotinate acetone hydrazone (SANH; S-HyNic) is a heterobifunctional linker used

for introducing protected hydrazinonicotinimide functional groups into proteins, peptides, surfaces and other

primary amine containing molecules via its reactive N-hydroxysuccinimide ester terminus. Upon

deprotection of the hydrazone functionality under acidic or neutral pH (4.5-7.4), the liberated hydrazine group

can then react with aldehydes and ketones to form stable bonds. SANH has also been used extensively for

the labeling of biomolecules with the SPECT imaging isotope, 99mTc [1-4].

Chemical Formula:

 

C15H18N4O6

CAS No.:

 

133081-26-2

Molecular weight:

 

350.33

Purity:

 

> 95% (HPLC)