iPSc from patient diagnosed with Izochromosome X
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iPSc from patient diagnosed with Izochromosome X
X isochromosome (iso(Xq)) is one of the causes of Turner Syndrome, which is characterized by short stature and loss of ovarian function. This condition affects 1 in 2500-3000 born girls. Additionally, isochromosome X may be associated with predisposition to autoimmune diseases such as Hashimoto’s thyroiditis, celiac disease, Crohn’s disease and other. iPSC generated from cells obtained from patient with iso(Xq) may serve as an in vitro disease model due to their ability to differentiate into cells of thyroid, intestine and others.
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▣ 관련 페이지 ; Celther Polska
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