FormuMax Scientific
 
작성일 : 13-11-08
[FormuMax Scientific] Drug Loaded Liposomes
Drug Loaded Liposomes
 
FormuMax offers a list of pharmaceutical actives encapsulated in liposomes. Currents products is shown in the list below
and we will continue to add more products in the future depending on the demand.
 
 
Doxoves® -  PEGylated Liposomal Doxorubicin HCl
 
Doxorubicin HCl is loaded into PEGylated liposomes composed of HSPC/CHOL/mPEG2000-DSPE (56.2:38.5:5.3 mol/mol)
with ammonium gradient by the active loading approach. It is comparable to the commercial product DOXIL®.  The
liposomes are prepared to very high quality with consistent lot-lot characteristics. Narrow particle size distribution and high
drug encapsualtion efficiency.  Note the high drug concentration (4mg/mL compared to 2 mg/mL for DOXIL®)  allows
the researchers to perform experiments at higher concentration/doses.
 
Cryo-EM of FormuMax's liposome doxorubicin HCl (F30204B-D) (Image taken by NanoImaging Services Inc.)
 
 
PEGylated Liposomal Irinotecan HCl
 
Irinotecan HCl is loaded into PEGylated liposomes composed of HSPC/CHOL/mPEG2000-DSPE (50:45:5 mol/mol) with
ammonium gradient by the active loading approach. The liposomes are produced by the extrusion method. The product
is of high quality with narrow particle size distribution and high drug encapsualtion efficiency.
 
 
PEGylated Liposomal Topotecan HCl
 
Topotecan HCl is loaded into PEGylated liposomes composed of HSPC/CHOL/mPEG2000-DSPE (50:45:5 mol/mol) with
ammonium sulfate gradient by the active loading approach. The liposomes are produced by the extrusion method. The
product is of high quality with Narrow particle size distribution and high drug encapsualtion efficiency.
 
 
 
 
  
 
Ordering informations
 
Catalog No.
Product Name
Size
Doxoves® - STEALTH Liposomal Doxorubicin HCl (4.0 mg/mL)
2 ml & 10 ml
STEALTH Liposomal Irinotecan HCl (2.0 mg/mL)
2 ml & 10 ml
STEALTH Liposomal Topotecan HCl (2.0 mg/mL)
2 ml & 10 ml
 
 
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