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작성일 : 21-03-02
[MTTI] Crosslinkers

 

Crosslinkers

 

SANH

Succinimidyl 6-hydrazinonicotinate acetone hydrazone (SANH; S-HyNic) is a heterobifunctional linker used

for introducing protected hydrazinonicotinimide functional groups into proteins, peptides, surfaces and other

primary amine containing molecules via its reactive N-hydroxysuccinimide ester terminus. Upon

deprotection of the hydrazone functionality under acidic or neutral pH (4.5-7.4), the liberated hydrazine group

can then react with aldehydes and ketones to form stable bonds. SANH has also been used extensively for

the labeling of biomolecules with the SPECT imaging isotope, 99mTc [1-4].

  

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Chemical Formula:

 

C13H14N4O4

CAS No.:

 

362522-50-7

Molecular weight:

 

290.27

Purity:

 

>90% by 1H NMR

Solubility:

 

>50mg/mL in DMF

 

Succinimidyl-Hynic hydrochloride

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Chemical Formula:

 

C10H10N4O4 . HCl

CAS No.:

 

133081-27-3

Molecular weight:

 

286.67

Purity:

 

> 95% (HPLC)

White to yellowish solid

 

Succinimidyl-N-Boc-Hynic

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Chemical Formula:

 

C15H18N4O6

CAS No.:

 

133081-26-2

Molecular weight:

 

350.33

Purity:

 

> 95% (HPLC)

   

 

Ordering informations

  

Catalog No.

Product Name

Size

SANH

10 & 25 mg

 FC-3410

Succinimidyl-Hynic hydrochloride

10 , 50  & 100 mg

FC-3420

Succinimidyl-N-Boc-Hynic

10, 100 mg & 1 g

 

 

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