Immudex ApS
 
작성일 : 18-04-17
[Immudex ApS] Dcode Dextramer, a DNA barcode added
Identify disease-specific T cells using unique DNA barcodes

 

Dcode Dextramer, adding a DNA barcode to the MHC Dextramer reagent

Identify disease-specific T cells using unique DNA barcodes

 

 

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MHC Dextramer reagents are used to identify disease-specific T cells in cell samples by flow cytometry.

The dCODETM Dextramer is a new technology adding a DNA barcode to the MHC Dextramer reagent,

allowing detection of antigen-specific T cells in cell samples by PCR followed by next generation

sequencing.

 

 

Key Features of dCODETM Dextramer;

• Identifies antigen-specific T cells based on TCR recognition

• Unique barcode label for each specificity

• High-throughput screening

• Applicable in Next Generation Sequencing assays

• dCODETM Dextramer reagents are available as single reagents and in packages

 

 

The dCODETM Dextramer technology provides a new understanding of T-cell immunology in cancer,

allergy, infectious, and autoimmune disease.

 

Applications;

• Biomarker assays

• Epitope discovery

• Neo-antigen identification

• Clinical immune monitoring

• Patient stratification

 

 

Reference;

Bentzen, AK. et al. "Large-scale detection of antigen-specific T cells using peptide-MHC-I multimers labeled

with DNA barcodes", Nature Biotechnology (2016)

 

 

Ordering information    

Catalog No.

Product Name

Size

N/A

Dcode Dextramer

25 tests, 50 tests, 150 tests

&  (5/10/25/50 x 25 tests)

 

 

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