CD1d Dextramer, reagent for monitoring NKT cells
CD1d Dextramers are flow cytometry reagents for identification and sorting of Natural Killer T (NKT) cells.
The number and function of NKT cells play an important role in regulating the immune response in many
autoimmune diseases, cancer, graft versus host disease, inflammation and various infectious diseases.
The CD1d/α-GalCer Dextramers displays CD1d molecules loaded with α-GalCer, or without a unique lipid,
unloaded CD1d. Both human and mouse CD1d can stain cells of mouse and human origen, although not
identical NKT cell populations are found between species.
• Superior separation
• High stability
• Reproducible results
• Quality controled
• Available with FITC, PE and APC.
Human CD1d: Cat. No. XD8002
Mouse CD1d: Cat. No. YD8002
* The CD1d/α-GalCer Dextramer displays CD1d molecules loaded with the glyco-lipid, α-GalCer.
Human CD1d: Cat. No. XD8001
Mouse CD1d: Cat. No. YD8001
* Load your lipid of interest to generate a unique CD1d/lipid Dextramer. Can be used as negative control
reagent. The CD1d/unloaded Dextramer reagent displays CD1d molecules without loaded lipid antigen.
Protocol for loading of lipids into CD1d_unloaded Dextramers (PDF)
Human CD1d Dextramer labled with either FITC, PE AND APC
Detection of NKT cells in human PBMCs using CD1d/α-GalCer Dextramers labeled with FITC, PE and APC
Mouse CD1d Dextramer labled with PE
Detection of NKT cells in Mouse CD4 positive splenocytes using mCD1d/α-GalCer Dextramers labeled