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작성일 : 17-07-11
[Immudex ApS] CD1d Dextramer, reagent for monitoring NKT cells

 

CD1d Dextramer, reagent for monitoring NKT cells

 

 

CD1d Dextramers are flow cytometry reagents for identification and sorting of Natural Killer T (NKT) cells.

The number and function of NKT cells play an important role in regulating the immune response in many

autoimmune diseases, cancer, graft versus host disease, inflammation and various infectious diseases.

 

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The CD1d/α-GalCer Dextramers displays CD1d molecules loaded with α-GalCer, or without a unique lipid,

unloaded CD1d. Both human and mouse CD1d can stain cells of mouse and human origen, although not

identical NKT cell populations are found between species.

 

 

Features;

 Superior separation

 High stability

 Reproducible results

 Quality controled

 Available with FITC, PE and APC.

 

 

CD1d/α-GalCer Dextramer:

Human CD1d: Cat. No. XD8002

Mouse CD1d: Cat. No. YD8002

* The CD1d/α-GalCer Dextramer displays CD1d molecules loaded with the glyco-lipid, α-GalCer.

 

CD1d/unloaded Dextramer:

Human CD1d: Cat. No. XD8001

Mouse CD1d: Cat. No. YD8001

* Load your lipid of interest to generate a unique CD1d/lipid Dextramer. Can be used as negative control

  reagent. The CD1d/unloaded Dextramer reagent displays CD1d molecules without loaded lipid antigen.

 

 

Protocol for loading of lipids into CD1d_unloaded Dextramers (PDF)

 

 

Human CD1d Dextramer labled with either FITC, PE AND APC

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Detection of NKT cells in human PBMCs using CD1d/α-GalCer Dextramers labeled with FITC, PE and APC

fluorochromes, respectively.

 

 

Mouse CD1d Dextramer labled with PE

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Detection of NKT cells in Mouse CD4 positive splenocytes using mCD1d/α-GalCer Dextramers labeled

with PE.

 

 

 

Ordering informations

    

Catalog No.

Product Name

Size

XD8002

CD1d/α-GalCer Dextramer, Human CD1d

15, 50, 150, 500 & 1000 tests

YD8002

CD1d/α-GalCer Dextramer, Mouse CD1d

15, 50, 150, 500 & 1000 tests

XD8001

CD1d/unloaded Dextramer, Human CD1d

15, 50, 150, 500 & 1000 tests

YD8001

CD1d/unloaded Dextramer, Mouse CD1d

15, 50, 150, 500 & 1000 tests

 

 

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