작성일 : 17-03-28
[G-Biosciences] Apotosis Inducers sets


Apotosis Inducers sets



Apoptosis is commonly defined as programmed mechanism of cell death and is a highly regulated process

that can be initiated by a variety of internal and external stimuli (inducers). G‐Biosciences’ Apoptosis

Inducers are ready‐to‐use solutions for inducing apoptosis in various cell types. They are supplied

individually as well as in a set of 6 inducers. These inducers include: Actinomycin D, Camptothecin,

Cycloheximide, Dexamethasone, Doxorubicin and Etoposide and can be used in 1000X dilution. These

agents induce apoptosis by different mechanisms. Depending on the need, individual as well as set of

inducers may be ordered.



Actinomycin D


클릭하시면 닫힙니다.이미지 저장을 원하시면 마우스 오른쪽클릭후 '다른이름으로 저장'을 하세요


A class of polypeptide antibiotics isolated from the Steptomyces soil bacteria.  Actinomycin D inhibits

transcription by binding to DNA at the transcription initiation complex and therefore preventing elongation by

the RNA polymerase.  




• Synonym : Dactinomycin

• CAS Number : 50-76-0

• Linear Formular : C62H86N12O16

• Molecular Weight : 1255.42




Bancos, S. et al (2010) Cell. Immunol. 262:18

Fenjves, E.S. et al (2008) Cell Transplant. 17:793

Vigneswaran, N. et al (2003) Oral Oncol. 39:559





클릭하시면 닫힙니다.이미지 저장을 원하시면 마우스 오른쪽클릭후 '다른이름으로 저장'을 하세요

A cytotoxic quinoline alkaloid that inhibits the DNA enzyme topoisomerase I (Topo I).





클릭하시면 닫힙니다.이미지 저장을 원하시면 마우스 오른쪽클릭후 '다른이름으로 저장'을 하세요


An inhibitor of protein synthesis by interfering with the translocation step (movement of two tRNA molecules

and mRNA on ribosome) in protein synthesis, thus blocking translational elongation.





클릭하시면 닫힙니다.이미지 저장을 원하시면 마우스 오른쪽클릭후 '다른이름으로 저장'을 하세요


A potent and stable glucocorticoid steroid hormone that is often used as an anti-inflammatory and anti-

rheumatic drug. The mechanism of action is not fully understood, however it is thought that it may inhibit

prostaglandin synthesis.






Doxorubicin (or hydroxyldaunorubicin) is an anthracycline antibiotic that intercalates DNA, inhibiting the

unwinding of DNA by topoisomerase II.





클릭하시면 닫힙니다.이미지 저장을 원하시면 마우스 오른쪽클릭후 '다른이름으로 저장'을 하세요


An inhibitor of topoisomerase II.



Instruction sheet (PDF)



Ordering informations    

Catalog No.

Product Name



Actinomycin D (10mM)

1 x 50 μl


Camptothecin (2mM)

1 x 1 ml


Cycloheximide (100mM)

1 x 1 ml


Dexamethasone (10mM)

1 x 1 ml


Doxorubicin (2mM)

1 x 50 μl


Etoposide (100mM)

1 x 50 μl


Apoptosis Inducer Set

Set of all 6 inducers



▣ 관련 페이지 ; G-Biosciences