Biotech Support Group
 
작성일 : 15-09-07
[Biotech Support Group] Protein Removal for Drug Binding/Screening & Metabolomics

 

BindPro™ Protein Removal for Drug Binding/Screening and Metabolomics

BindPro can eliminate the artifacts of protein contamination and improve study of amino acids, sugars,

lipids, nu-cleotides, and other biomolecules from biological tissues and fluids.

 

 

BindPro™ is a polymeric protein removal suspension reagent. It is designed as an alternative to ultrafiltration

for applications that require a more versatile or scaleable format. BindPro™ also can be used in lieu of

solvents for drug binding studies, especially useful for analytes that are water soluble. Consequently,

BindPro™ has applications in a range of drug binding, screening and metabolomic investigations.If desired,

proteins can be recovered from BindPro™ under moderately alkaline conditions.

 

 

Features

Serum and plasma protein removal, >95%

Applicable for drug binding/screening, metabolomics and protein recovery

Linearly scaleable, unlike ultrafiltration

Suitable for use with surfactants, chaotropes, water-soluble analytes

Fast process, less than 15 minutes from application to separation

 

 

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Lane 1: Plasma control

 

Lane 2: Plasma after treatment with BindPro™

* Note: Protein bands are not present indicated quantitative protein binding to

           BindPro™ surface.

 

Lane 3: Eluent from BindPro™

* Note: If necessary, proteins bound can be quantitatively recovered from BindPro™.

 

 

Reference

Lipoproteins

Turner, Joseph D., R. Stuart Langley, Kelly L. Johnston, Katrin Gentil, Louise Ford, Bo Wu, Maia Graham et

al. "Wolbachia lipoprotein stimulates innate and adaptive immunity through Toll-like receptors 2 and 6 to induce disease manifestations of filariasis." Journal of Biological Chemistry 284, no. 33 (2009): 22364-22378.

 

 

  

Ordering informations

   

Catalog No.

Product Name

Size

BP355-15 (PDF)

BindPro™, 75 samples, 100μl serum sample

15 ml

BP355-50 (PDF)

BindPro™, 250 samples, 100μl serum sample

50 ml

 

 

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