FormuMax Scientific
 
작성일 : 12-08-13
[FormuMax Scientific] Pre-formed Liposomes
전달 연구에 유용한 각종 리포솜입니다. 모든 필터 멸균에서 입경이 균일하기 때문에 로트 간의 차이도 적고, 고품질의 제품입니다.
Pre-formed Liposomes
약물 전달 연구에 유용한 각종 리포솜입니다. 모든 필터 멸균에서 입경이 균일하기 때문에 로트 간의 차이도 적고, 고품질의 제품입니다.
 

FormuMax offers pre-formed liposome reagents to research organizations involved in liposomal drug delivery. We offer a
large number of common lipid compositions, prepared by experienced formulators using only the highest quality lipids
from premier suppliers. Our products are easy to use, time-saving, and cost-saving, improving the productivity and
reliability of your research. They are highly trustworthy for batch-to-batch consistency and reproducibility, and are sterile-
filtered and properly packaged in vials to ensure long-term stability when stored refrigerated.
 
Please feel free to contact us if you do not find the specific preformed liposome of your interest. We also provide custom liposomes made to your specifications.
 
 
 
 
A. Empty (Plain) Non-PEGylated Liposomes

Extrusion 법에 의해 제작된 지질이중막으로 구성된 liposome 입니다. 자당과 HEPES를 포함 수용액에서 수화되어 있습니다. 구성 지질 콜레스테롤을 포함한 제품과 포함하지 않는 제품이 있습니다. 화합물을 내포한 리포솜의 컨트롤로 사용할 수 있습니다.
 
Liposomes composed of a bilayer-forming phospholipid with/without cholesterol and prepared by the extrusion method. This series of plain liposomes is prepared by hydration in sucrose/HEPES solution and contains NO drug loading battery. All products are sterile filtered and filled in autoclaved glass vials. 
 
 
Ordering information ;
  
Catalog No.
Product Name
Size
F10102 (PDF)
Plain DPPC/CHOL liposomes (55:45 mol/mol, 100 nm)
10 ml
F10103 (PDF)
Plain DSPC/CHOL liposomes (55:45 mol/mol, 100 nm)
10 ml
F10103B (PDF)
Plain DSPC/CHOL Liposomes (67:33 mol/mol, 100 nm)
10 ml
Plain small sized DSPC/CHOL Liposomes (67:33 mol/mol, 80 nm)
10 ml
F10104 (PDF)
Plain HSPC/CHOL Liposomes (55:45 mol/mol, 100 nm)
10 ml
F10105 (PDF)
Plain 20:0PC/CHOL Liposomes (55:45 mol/mol, 100 nm)
10 ml
F10106 (PDF)
Plain 22:0PC/CHOL Liposomes (55:45 mol/mol, 100 nm)
10 ml
F10107 (PDF)
Plain 24:0PC/CHOL Liposomes (55:45 mol/mol, 120 nm)
10 ml
F10108 (PDF)
Plain PHSPC/CHOL Liposomes (55:45 mol/mol, 100 nm)
10 ml
F10109 (PDF)
Plain Pure DOPC Liposomes (100 nm)
10 ml
F10110 (PDF)
Plain Pure POPC Liposomes (100 nm)
10 ml
 
 
 
B. Empty (Plain) PEGylated Liposomes
 
PEG (Polyethylene glycol) 수식 liposome 입니다. Sucrose, HEPES, Ethanol 을 포함하는 수용액에서 수화되어 있습니다.
구성 지질에 cholesterol를 함유하는 제품과 함유하지 않는 제품이 있습니다.
 
Liposomes composed of a bilayer-forming phospholipid and mPEG-DSPE with/without cholesterol and prepared by the
extrusion method. This series of plain liposomes is prepared by hydration in sucrose solution and contains NO drug loading battery.  All products are sterile filtered and filled in autoclaved vials.     
 
 
 
 
 
Ordering information ;
 
Catalog No.
Product Name
Size
F10202 (PDF)
Plain DPPC/CHOL/mPEG2000-DSPE Liposomes (50:45:5 mol/mol, 100 nm)
10 ml
F10203 (PDF)
Plain DSPC/CHOL/mPEG2000-DSPE Liposomes (50:45:5 mol/mol, 100 nm)
10 ml
F10204 (PDF)
Plain HSPC/CHOL/mPEG2000-DSPE Liposomes (50:45:5 mol/mol, 100 nm)
10 ml
F10205 (PDF)
Plain 20:0PC/CHOL/mPEG2000-DSPE Liposomes (50:45:5 mol/mol, 100 nm)
10 ml
F10206 (PDF)
Plain 22:0PC/CHOL/mPEG2000-DSPE (50:45:5 mol/mol) Liposomes (110 nm)
10 ml
F10207 (PDF)
Plain 24:0PC/CHOL/mPEG2000-DSPE Liposomes (50:45:5 mol/mol, 120 nm)
10 ml
 
 
 
C. Ammonium Gradient Liposomes for Active Loading
 
황산 암모늄 수용액에서 수화하여 막분리 여과하여, sucrose 용액에 다시 현탁한 liposome 입니다. 약 염기성의 화합물을
liposome 에 내포시킬 수 있습니다.  수식되지 않은 제품과 PEG로 수식된 제품이 있습니다.
 
The most commonly used liposomes for active (remote) loading of weakly basic small molecules contain transmembrane
ammonium sulfate gradient as the drug loading battery. These liposomes are hydrated with an ammonium sulfate
solution. After down-sizing by extrusion, the transmembrane ammonium gradiant is generated by exchanging the external ammonium sulfate against a 10% sucrose solution. All products are sterile filtered and filled in autoclaved glass vials.
Loading is as simple as mixing the drug and liposomes at desired ratio and incubate at 65 deg C for 30-60min.  
 
We also provide liposomes with other types of batteries, such as ammonium dextran sulfate, ammonium octasucrose
sulfate. citric acid etc. Please contact us for details.
 
 
 
 
 
 
(Ammonium Gradient Liposome)
 
 
 
Ordering information ;
 
Catalog No.
Product Name
Size
F20103A (PDF)
DSPC/CHOL (55:45 mol/mol) Liposomes with Ammonium Gradient (100nm)
10 ml
F20104A (PDF)
HSPC/CHOL (55:45 mol/mol) Liposomes with Ammonium Gradient (100nm)
10 ml
F20202A (PDF)
DPPC/CHOL/mPEG2000-DSPE (50:45:5 mol/mol) Liposomes with
 Ammonium Gradient (100nm)
10 ml
F20203A (PDF)
DSPC/CHOL/mPEG-DSPE (50:45:5 mol/mol) Liposomes with
Ammonium Gradient (100nm)
10 ml
 
 
 
 
(Ammonium Gradient PEGylated Liposome)
 
 
 
Ordering information ;
 
Catalog No.
Product Name
Size
F20204A (PDF)
HSPC/CHOL/mPEG2000-DSPE (50:45:5 mol/mol) Liposomes with
Ammonium Gradient (100nm)
10 ml
F20204A (PDF)
HSPC/CHOL/mPEG2000-DSPE (56.2/38.5/5.3) Liposomes with
Ammonium Gradient (100nm)
10 ml
F20204A (PDF)
SUV HSPC/CHOL/mPEG2000-DSPE (56.2/38.5/5.3) Liposomes with
Ammonium Gradient (80 nm)
10 ml
F20205A (PDF)
20:0 PC/CHOL/mPEG2000-DSPE (50:45:5 mol/mol) Liposomes with
Ammonium Gradient (110nm)
10 ml
F20206A (PDF)
22:0 PC/CHOL/mPEG2000-DSPE (50:45:5 mol/mol) Liposomes with
Ammonium Gradient (110nm)
10 ml
F20207A (PDF)
24:0 PC/CHOL/mPEG2000-DSPE (50:45:5 mol/mol) Liposomes with
Ammonium Gradient (120nm)
10 ml
 
 
 
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