Hemoglobin Removal White paper Describes a Range of Depletion Strategies and
Their Successful Uses
MONMOUTHJUNCTION, NJ, May 8, 2020 -- Biotech Support Group reports on a White paper describing
the simplicity and efficiency of their hemoglobin depletion technology in a diverse range of applications
including the annotation of the red cell proteome, the identification of drug-target interactions, and
the removal of a variety of analytical interferences.
The White paper is entitled:
Removal - The Gold Standard Products”,
April 28, 2020
Hemoglobin accounts for ≥ 95% of the protein mass in erythrocytes, and is often an interfering factor
for many types of analysis, both proteinaceous(i.e., immunoassay) and non-proteinaceous (i.e., PCR).
With the rising use of dried blood cards and point-of-care devices, analytical interferences
from Hemoglobin continues to present problems. BSG products offer a simple and efficient solution for
Hemoglobin removal in a variety of separation strategies and formats. Out of the 40+ citations for
these products, the White paper highlights some of the more definitive examples of how Hemoglobin
depletion improved the value of the research investigation. Successful uses are described for diseases
such as Malaria and Parkinsons Disease, as well as drug-target interactions and post-translational
modifications discovered from erythrocyteproteomes. Sample types include erythrocyte lysates,
hemolyzed serum, wholeblood, and dried blood cards. The BSG application specific products
are especially designed for all these challenges.
“We now know that red cells carry more than just oxygen, and cooperate in some way with the other
blood compartments. With the efficiency of Hemoglobin removal that our products provide,
investigators cannow study the many aspects of red cells as they relate to disease. Finally, we can
provide a simple method to remove Hemoglobin interference, as this canoften be a problem with more
routine clinical analysis. This is becoming especially important with the growing use of dried blood cards
and point-of-care devices”, states Swapan Roy, Ph.D., President and Founder of Biotech Support Group.
For more information on all of our Hemoglobin removal products,