작성일 : 17-01-26
Article in Red Blood Cell Proteome Study
 글쓴이 : 운영자
 

 

Research Article Cites HemoVoid™ in Red Blood Cell Proteome Study

 

 

MONMOUTH JUNCTION, NJ, January 23, 2017 -- Biotech Support Group reports on a recent research article

describing the simplicity and efficiency of theirhemoglobin depletion technology for enriching the red cell sub-

proteome, fromhuman red blood cells.  The citation is:

 

Feliciano, Amélia, et al. "Evening and morning alterations in Obstructive Sleep Apnea red blood cell proteome."

Data in Brief (2017).  http://dx.doi.org/10.1016/j.dib.2017.01.005

 

In brief, using proteomics-based evaluation of red blood cells (RBC), the authors identifieddifferentially abundant

proteins associated with Obstructive Sleep ApneaSyndrome (OSA). Proteome variations between various time

points were assessed.The article states “RBC cytoplasmic fraction depleted of hemoglobin, usingHemovoid™

system, were analyzed by two-dimensional fluorescence difference gelelectrophoresis (2D-DIGE), the 2D image

software-based analyzed and relevantdifferentially abundant proteins identified by mass spectrometry (MS)”. The

authors conclude that 31protein spots were differentially abundant,corresponding to 21 unique proteins possibly

due to the existence ofpost-translational modifications.

 

“This article illustrates the importance of removing hemoglobin in order to performproteomic analysis of red cells.

The ability to enrich for the underlyingsub-proteome which would normally mask many proteins from red cells is a

uniquefeature of HemoVoid™. That many differentially regulated proteins wereidentified demonstrates its

usefulness in proteomic investigations” statesSwapan Roy, Ph.D., President and Founder of Biotech Support Group.

For more information on HemoVoid™, visit:

http://www.biotechsupportgroup.com/HemoVoid-Hemoglobin-Depletion-From-Erythrocytes-p/hvk.htm

 

 

Contact:

Matthew Kuruc 732-274-2866, mkuruc@biotechsupportgroup.com

 

 

 

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