Article Cites HemoVoid™ in Red Blood Cell Proteome Study
JUNCTION, NJ, January 23, 2017 -- Biotech
Support Group reports on a recent research article
describing the simplicity and efficiency of theirhemoglobin depletion technology for enriching the red cell sub-
proteome, fromhuman red blood cells. The citation is:
Feliciano, Amélia, et
al. "Evening and morning alterations in Obstructive Sleep Apnea red blood
Data in Brief (2017). http://dx.doi.org/10.1016/j.dib.2017.01.005
In brief, using
proteomics-based evaluation of red blood cells (RBC), the authors identifieddifferentially abundant
proteins associated with Obstructive Sleep ApneaSyndrome (OSA). Proteome variations between various time
points were assessed.The article states “RBC cytoplasmic fraction depleted of hemoglobin, usingHemovoid™
system, were analyzed by two-dimensional fluorescence difference gelelectrophoresis (2D-DIGE), the 2D image
software-based analyzed and relevantdifferentially abundant proteins identified by mass spectrometry (MS)”. The
authors conclude that 31protein spots were differentially abundant,corresponding to 21 unique proteins possibly
due to the existence ofpost-translational modifications.
article illustrates the importance of removing hemoglobin in order to performproteomic analysis of red cells.
The ability to enrich for the underlyingsub-proteome which would normally mask many proteins from red cells is a
uniquefeature of HemoVoid™. That many differentially regulated proteins wereidentified demonstrates its
usefulness in proteomic investigations” statesSwapan Roy, Ph.D., President and Founder of Biotech Support Group.
For more information
on HemoVoid™, visit:
Matthew Kuruc 732-274-2866, firstname.lastname@example.org