작성일 : 16-03-02
Research Article Cites Cleanascite for Alzheimer’s Disease Biomarkers
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Research Article Cites Cleanascite™ for Alzheimer’s Disease Biomarkers

 

 

MONMOUTH JUNCTION, N.J. – Sept. 17, 2015 – PRLog — MONMOUTH JUNCTION, NJ — Biotech Support

Group reports on a recent research article describing the simplicity and efficiency of their proteomic sample

preparation technology for clearing lipoproteins from human sera.

The citation is:

John A. McIntyre, Curtis J. Ramsey, Bruce D. Gitter,Andrew J. Saykin, Dawn R. Wagenknecht, Paul A. Hyslop.

Antiphospholipid autoantibodies as blood biomarkers for detection of early stage Alzheimer’s disease.

Autoimmunity, 2015; 48(5): 344-351. DOI: 10.3109/08916934.2015.1008464

 

In brief, the article’s authors aimed at identifying new biomarkers for early diagnosis of Alzheimer’s disease,

by ELISA measurement of redox reactive autoantibodies (R-RAAs) antiphospholipid antibodies. The article

states “Aliquots of the 90 ADNI serum samples were thawed and treated with Cleanascite™ (Biotech Support

Group) at a serum: Cleanascite™ ratio of 4:1 v/v in 2 ml micro centrifuge tubes with gentle rocking at 37°C for

10min followed by centrifugation for 1 min at 16 000g. Treatment with Cleanascite™ removes lipoproteins from

the serum, which have been shown to bind and undergo oxidation with hemin.”

“This is an excellent example of how Cleanascite™ can improve ELISA measurements. Clearly, there was

necessity for removing lipoproteins without compromising the quantity or quality of the autoantibodies present

and to be measured. The exquisite selectivity profile of Cleanascite™ makes this possible.” states Swapan

Roy, Ph.D., President and Founder of Biotech Support Group.

For more information visit: Cleanascite™ Lipid Removal Reagent and Clarification, at

http://www.biotechsupportgroup.com/cleanascite-lipid-remo

 

 

About Biotech Support Group LLC

Biotech Support Group LLC is a leading provider of proteomic, metabolomic and genomic sample preparation

and enrichment products and services. It’s principal products include: AlbuVoid™ & AlbuSorb™ for albumin

depletion, Cleanascite™ for lipid adsorption and clarification, HemogloBind™ & HemoVoid™ for hemoglobin

removal, NuGel™ for functional & chemical proteomics, and ProCipitate™ for nucleic acid isolation. For more

information, go to http://www.biotechsupportgroup.com

 

 

   

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